| |
|
|
|
|
|
|
|
|
|
|
|
|
|
| mAb to O2-ethyl-deoxythymidine (EM 4-1) |
| |
| |
Product Data |
|
Graphics |
|
Product Flyer |
|
References |
|
|
|
|
|
|
| |
| |
|
|
|
|
|
| Request info |
| |
| |
|
|
| | Product Name | mAb to O2-ethyl-deoxythymidine (EM 4-1) |
|
| | Synonyms | EM 4-1 monoclonal antibody |
|
| | Catalog No | SQM015.1 |
|
| | Size | 200 µg |
|
| | Price | 375,00 EUR |
|
| | Category | Antibodies and Conjugates |
|
| | Description | monoclonal antibody, specific for O2-ethyl-deoxythymidine |
|
| | Background | DNA-lesion specific monoclonal antibody |
|
| | Feature | Detects a specific mutagenic DNA modification induced by several exogenous and endogenous carcinogens e.g. food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens; Molecular epidemiology of carcinogen exposure; Pre- and intratherapeutic dosimetry of exposure to anticancer agents; Basic research of molecular mechanisms of carcinogenesis; Mutagenicity testing of substances |
|
| | Molecular Weight | 160 kDa |
|
| | Presentation | lyophilized |
|
| | Reconstitution | reconstitute with 1 ml of PBS, 0.05% sodium azide, 1% bovine serum albumine |
|
| | Stabilizer | none |
|
| | Storage | -20°C |
|
| | Applications | Competitive Radioimmunoassay, Immunodytochemistry: 2-5 µg/ml PBS with 3% BSA |
|
| | Characteristics | specifically reacts with O2-ethyl-deoxythymidine in human, mouse, rat |
|
| | Host | mouse |
|
| | Isotype | IgG1 |
|
| | Clonality | monoclonal |
|
| | Clone | EM 4-1 |
|
| | Immunogen | O2-ethyl-deoxythymidine-Thyroglubulin conjugate |
|
| | Specificity | O2-ethyl-deoxythymidine |
|
| | Cross Reactions | see RIA specifity table (see graphics) |
|
| | Affinity Constant | 1.6 x 10 e9 (l/Mol) |
|
| | Purification | Protein G affinity purification from cell culture supernatant |
|
| | Purity | >95% |
|
| | Working Dilution | test dependent |
|
| | Expiry | 1 year |
|
| | Considerations for Use | Please store the vial at 4-8 deg. C. The product is stable for 1 year at 4-8 deg. C in its stock solution. Working dilutions should always be prepared freshly. For extended storage of the stock solution please add 50% glycerol and freeze the product. |
|
| |
