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HYDRA-O6-ethyl-2-deoxyguanosine immunoaffinity support |
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Product Data |
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Product Flyer |
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References |
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Request info |
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Product Name |
HYDRA-O6-ethyl-2-deoxyguanosine immunoaffinity support |
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Catalog No |
SQCM001 |
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Size |
1 ml |
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Price |
845,00 EUR |
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Category |
Antibody affinity supports |
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Description |
HYDRA support for immunoaffinity purification of O6-ethyl-2-deoxyguanosine from biological samples |
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Feature |
Isolates a specific mutagenic DNA modification induced by several exogenous and endogenous carcinogens e.g. food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens; Molecular epidemiology of carcinogen exposure; Pre- and intratherapeutic dosimetry of exposure to anticancer agents; Basic research of molecular mechanisms of carcinogenesis; Mutagenicity testing of substances |
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Appearance |
mAb immobilized to HYDRA immunochromatographic support |
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Presentation |
gel slurry in PBS, 0.05% sodium azide |
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Stabilizer |
none |
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Storage |
4°C |
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Applications |
immunopurification of biological samples |
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Characteristics |
binding capacity: approx. 1-3 x e-9 Mol / ml polymethacrylate support |
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Host |
rat |
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Isotype |
rat IgG2b |
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Clonality |
monoclonal |
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Clone |
ER 6 |
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Specificity |
O6-ethyl-2-deoxyguanosine |
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Cross Reactions |
see RIA specifity table (see graphics) |
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Affinity Constant |
2.0 x 10 e10 (l/Mol) |
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Purification |
mAb purified by Protein G from cell culture supernatant |
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Expiry |
3 years |
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Considerations for Use |
Please store the vial at 4-8 deg. C. The product is stable for 3 years at 4-8 deg. C. |
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Protocol |
see references |
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Keywords |
mutagenic DNA-modification; mAb, monoclonal antibody to modified DNA-base; mutagenicity testing, cacinogenesis, intratherapeutic dosimetry, molecular epidemiology; DNA-adduct; O-alkyl adduct detection in DNA, HYDRA immunoaffinity support |
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