kopfleiste_03_960.jpg
   
You are here: /mAb to O6-ethyl-2-deoxyguanosine (EM 21)
Details
 
> Antibodies & Proteins
 
> Antibodies & Conjugates
 
> Anti Human IgE Antibodies & Conjugates
 
> Proteins
 
> Antibody affinity supports
 
                           
mAb to O6-ethyl-2-deoxyguanosine (EM 21)
 
  Product Data   Graphics   Product Flyer   References            
 
         
Request info
 
     
  Product Name mAb to O6-ethyl-2-deoxyguanosine (EM 21)  
  Synonyms EM 21 monoclonal antibody  
  Catalog No SQM004.1  
  Size 50 µg  
  Price 375,00 EUR  
  Category Antibodies and Conjugates  
  Description monoclonal antibody, specific for O6-ethyl-2-deoxyguanosine  
  Background DNA-lesion specific monoclonal antibody  
  Feature Detects a specific mutagenic DNA modification induced by several exogenous and endogenous carcinogens e.g. food, smoking, cancer therapeutics, environmental carcinogens, workplace carcinogens; Molecular epidemiology of carcinogen exposure; Pre- and intratherapeutic dosimetry of exposure to anticancer agents; Basic research of molecular mechanisms of carcinogenesis; Mutagenicity testing of substances  
  Molecular Weight 160 kDa  
  Presentation lyophilized  
  Reconstitution reconstitute with 1 ml of PBS, 0.05% sodium azide, 1% bovine serum albumine  
  Stabilizer none  
  Storage -20°C  
  Applications Competitive Radioimmunoassay, ELISA, Immuno-Slot-Blot-Assay, Not suitable for Immunohistochemistry  
  Characteristics specifically reacts with O6-ethyl-2-deoxyguanosine in human, mouse, rat  
  Host mouse  
  Isotype IgG1  
  Clonality monoclonal  
  Clone EM 21  
  Immunogen O6-ethyl-2-deoxyguanosine-Thyroglubulin conjugate  
  Specificity O6-ethyl-2-deoxyguanosine  
  Cross Reactions see RIA specifity table (see graphics)  
  Affinity Constant 2.4 x 10 e10 (l/Mol)  
  Purification Protein G affinity purification from cell culture supernatant  
  Purity >95%  
  Working Dilution test dependent  
  Expiry 1 year  
  Considerations for Use Please store the vial at 4-8 deg. C. The product is stable for 1 year at 4-8 deg. C in its stock solution. Working dilutions should always be prepared freshly. For extended storage of the stock solution please add 50% glycerol and freeze the product.  
  Keywords mutagenic DNA-modification; mAb, monoclonal antibody to modified DNA-base; mutagenicity testing, cacinogenesis, intratherapeutic dosimetry, molecular epidemiology; DNA-adduct; O-alkyl adduct detection in DNA  
 
Contact legal notice